It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus. Omeprazole Magnesium is a medication commonly prescribed for the treatment of various gastrointestinal conditions. It belongs to a class of drugs known as proton pump inhibitors (PPIs) and works by reducing the production of stomach acid. It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole can cause low magnesium levels, also known as hypomagnesemia, which can be serious. Decreased magnesium levels can cause seizures or heart rhythm problems. Because there is a salt (magnesium) attached to the Omeprazole, it makes it easy to dissolve and can be taken on an empty stomach or with food. Whenever Omeprazole alone is taken, it should be taken prior to meals. Yes, you can take magnesium and omeprazole together – they do not dangerously react in the moment. The real issue is the other direction: long-term omeprazole can lower your magnesium, and it slightly reduces how much supplement magnesium you absorb. Omeprazole Magnesium Granules package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. An article published in 2013 claims that the long-term use of PPIs is associated with decreased calcium absorption (causing increased risk of osteoporosis and fractures), decreased magnesium absorption (causing electrolyte disturbances), and increased risk of certain infections, such as C. difficile and community-acquired pneumonia. Omeprazole is a medication that reduces the amount of acid in your stomach. It treats heartburn, stomach ulcers and reflux disease. Omeprazole is a proton pump inhibitor (PPI) that works by blocking the acid pump in your stomach, reducing how much acid it makes and giving irritated or damaged tissue a chance to heal. Omeprazole brand names are Prilosec, Prilosec OTC, and generic brands are available.